PERBANDINGAN HASIL INR (International Normalized Ratio) SEBELUM DAN SESUDAH TERAPI HEPARIN WARFARIN PADA PASIEN PENYAKIT JANTUNG KORONER DI RUMAH SAKIT ATMA JAYA JAKARTA UTARA

Heru Setiawan; Venna Venna; Lowisa Debora Turnip

doi:10.59946/jfki.2025.399

PERBANDINGAN HASIL INR (International Normalized Ratio) SEBELUM DAN SESUDAH TERAPI HEPARIN WARFARIN PADA PASIEN PENYAKIT JANTUNG KORONER DI RUMAH SAKIT ATMA JAYA JAKARTA UTARA

Heru Setiawan
Venna Venna
Lowisa Debora Turnip

DOI: https://doi.org/10.59946/jfki.2025.399

Keywords: : CHD, warfarin, INR

Abstract

Coronary Heart Disease (CHD) is a disorder of heart function due to a lack of blood in the heart muscle due to narrowing or blockage of the coronary arteries caused by atherosclerosis. This occurs when the heart muscle's supply of oxygen-rich blood is blocked by plaque in the blood vessels leading to the heart blood or coronary arteries. Warfarin is an anticoagulant that is strongly associated with bleeding in CHD. The laboratory examination that is often used to measure prothrombin time and as anticoagulant therapy to detect bleeding disorders is INR (International Normalized Ratio). This study aims to determine the comparison of INR results before and after heparin warfarin therapy in coronary heart disease patients at Atma Jaya Hospital. The method of this research is cross sectional descriptive analysis using 39 RM data from CHD patients who have met the inclusion and exclusion criteria using the Wilcoxon test. These results showed that the average INR value before therapy was 1.849 per second, the average INR value after therapy was 1.316 per second. The Wilcoxon test results showed a difference between INR values before and after therapy (p=0.000) with significance (α=<0.05) in patients on heparin warfarin therapy at Atma Jaya Hospital. From this research, it is hoped that CHD patients will continue to undergo therapy to prevent hemostasis disorders and to avoid the risk of bleeding which can cause death.

Keywords: CHD, warfarin, INR.

References

1. Harahap GA, Nurcahyo WI, Ismail A. Widya Istanto Nurcahyo. Akhmad Ismail JKD [Internet]. 2016;5(2):160–6. Available from: https://ayosehat.kemkes.go.id/peringatan-hari-jantung-sedunia-2021-jaga-jantungmu-untuk-hidup-lebih-sehat
2. Kemkes. kemkes.go.id. 2021 [cited 2024 Mar 14]. Peringatan Hari Jantung Sedunia 2021: Jaga Jantungmu untuk Hidup Lebih Sehat. Available from: https://ayosehat.kemkes.go.id/peringatan-hari-jantung-sedunia-2021-jaga-jantungmu-untuk-hidup-lebih-sehat
3. Roveny. Antikoagulan untuk Stroke Iskemik Kardioemboli, IAI Continuing Professional Development. 2015;42(5):345–9.
4. Agustini TT, Arifin H, Hanif AM. Comparison between Warfarin Dose with Duration Achieving Target INR in Patient with CHF and Atrial Fibrillation. J Sains Farm Klin [Internet]. 2016;2(2):162–70. Available from: http://jsfkonline.org/index.php/jsfk/article/view/67
5. Octasari PM, Silvianingsih N, Mangunwijaya PK. Kesesuaian Nilai INR ( International Normalized Ratio ) Pasien Kardiovaskuler Dengan Terapi Warfarin Di Poli Spesialis Jantung RS Roemani Muhammaddiyah This study aims to determine the suitability of the INR value in cardiovascular patients with warfarin . 2022;6(1):46–54.
6. Setiabudy RD. Hemostasis dan Trombisis Edisi Kelima, Fakultas Kedokteran Universitas Indonesia. Prosedur Penelit. 2012;
7. Andini R, Astuti YP. Klasifikasi Kelompok Umur Manusia Bedasarkan Analisis Dimensi Fraktal Box Counting Dari Citra Wajah Dengan Deteksi Tepi Canny. J Ilm Mat [Internet]. 2021;9(2):437–46. Available from: https://media.neliti.com/media/publications/249234-model-infeksi-hiv-dengan-pengaruh-percob-b7e3cd43.pdf
8. Aisyah, Ranggauni Hardy F, Pristya TY, Qoulan Karima U. Kejadian Penyakit Jantung Koroner Pada Pasien Di RSUD Pasar rebo. Higeia J Public Heal Res Dev [Internet]. 2022;6(4):250–60. Available from: http://journal.unnes.ac.id/sju/index.php/higeia
9. Vercayie D. Jurnal_Florence (Laki-laki dan Riwayat Keluarga PJK).pdf.
10. Melyani M, Tambunan LN, Baringbing EP. Hubungan Usia dengan Kejadian Penyakit Jantung Koroner pada Pasien Rawat Jalan di RSUD dr. Doris Sylvanus Provinsi Kalimantan Tengah. J Surya Med. 2023;9(1):119–25.
11. Arnett DK, Blumenthal RS, Albert MA, Buroker AB, Zachary D, Hahn EJ, et al. Erratum: 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines (Circulation. (2019) 140 (e596-e646) DOI: 10.1161/CIR. Vol. 141, Circulation. 2020. E774 p.
12. Kernan WN, Ovbiagele B, Black HR, Bravata DM, Chimowitz MI, Ezekowitz MD, et al. Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: A guideline for healthcare professionals from the American Heart Association/American Stroke Association. Vol. 45, Stroke. 2014. 2160–2236 p.
13. Bjective O. WARFARIN : MANAGEMENT OF OUT-OF-RANGE INRS. :2–7.
14. NCBI. National Center for Biotechnology Information (NCBI). PubChem Compound Warfarin. Dilihat 09 Maret 2024. [Internet]. 2011. p. ncbi.nlm.nih.gov. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/Warfarin
15. Medscape. Drug Interaction [Internet]. 2020. Available from: http://reference.medscape.com/druginteractionchecker

Published

2025-06-05

How to Cite

Setiawan, H., Venna, V., & Debora Turnip, L. (2025). PERBANDINGAN HASIL INR (International Normalized Ratio) SEBELUM DAN SESUDAH TERAPI HEPARIN WARFARIN PADA PASIEN PENYAKIT JANTUNG KORONER DI RUMAH SAKIT ATMA JAYA JAKARTA UTARA. Jurnal Fisioterapi Dan Kesehatan Indonesia, 5(01), 66-72. https://doi.org/10.59946/jfki.2025.399

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may reproduce or authorize others to reproduce the article, material extracted from the article, or derivative works for the author’s personal use or for company use, provided that the source and the copyright notice are indicated, the copies are not used in any way that implies RCEPM-LIPI endorsement of a product or service of any employer, and the copies themselves are not offered for sale.

All copies, print or electronic, or other use of the paper or article must include the appropriate bibliographic citation for the article’s publication in the journal.

2. Requests from third parties

Although authors are permitted to re-use all or portions of the article in other works, this does not include granting third-party requests for reprinting, republishing, or other types of re-use. Requests for all uses not included above, including the authorization of third parties to reproduce or otherwise use all or part of the article (including figures and tables), should be referred to RCEPM-LIPI by going to our website athttp://telimek.lipi.go.id.

3. Author Online Use

Personal Servers. Authors and/or their employers shall have the right to post the accepted version of articles pre-print version of the article, or revised personal version of the final text of the article (to reflect changes made in the peer review and editing process) on their own personal servers or the servers of their institutions or employers without permission from RCEPM-LIPI, provided that the posted version includes a prominently displayed RCEPM-LIPI copyright notice and, when published, a full citation to the original publication, including a link to the article abstract in the journal homepage. Authors shall not post the final, published versions of their papers;
Classroom or Internal Training Use. An author is expressly permitted to post any portion of the accepted version of his/her own articles on the author’s personal web site or the servers of the author’s institution or company in connection with the author’s teaching, training, or work responsibilities, provided that the appropriate copyright, credit, and reuse notices appear prominently with the posted material. Examples of permitted uses are lecture materials, course packs, e-reserves, conference presentations, or in-house training courses;
Electronic Preprints. Before submitting an article to an MEV Journal, authors frequently post their manuscripts to their own web site, their employer’s site, or to another server that invites constructive comment from colleagues. Upon submission of an article to MEV Journal, an author is required to transfer copyright in the article to RCEPM-LIPI, and the author must update any previously posted version of the article with a prominently displayed RCEPM-LIPI copyright notice. Upon publication of an article by the RCEPM-LIPI, the author must replace any previously posted electronic versions of the article with either (1) the full citation to the work with a Digital Object Identifier (DOI) or link to the article abstract in MEV journal homepage, or (2) the accepted version only (not the final, published version), including the RCEPM-LIPI copyright notice and full citation, with a link to the final, published article in journal homepage.

4. Articles in Press (AiP) service

RCEPM-LIPI may choose to publish an abstract or portions of the paper before we publish it in the journal. Please contact our Production department immediately if you do not want us to make any such prior publication for any reason, including disclosure of a patentable invention.

5. Author/Employer Rights

If you are employed and prepared the article on a subject within the scope of your employment, the copyright in the article belongs to your employer as a work-for-hire. In that case, RCEPM-LIPI assumes that when you sign this Form, you are authorized to do so by your employer and that your employer has consented to the transfer of copyright, to the representation and warranty of publication rights, and to all other terms and conditions of this Form. If such authorization and consent has not been given to you, an authorized representative of your employer should sign this Form as the Author.

6. RCEPM-LIPI Copyright Ownership

It is the formal policy of RCEPM-LIPI to own the copyrights to all copyrightable material in its technical publications and to the individual contributions contained therein, in order to protect the interests of the RCEPM-LIPI, its authors and their employers, and, at the same time, to facilitate the appropriate re-use of this material by others. RCEPM-LIPI distributes its technical publications throughout the world and does so by various means such as hard copy, microfiche, microfilm, and electronic media. It also abstracts and may translate its publications, and articles contained therein, for inclusion in various compendiums, collective works, databases and similar publications

Every accepted manuscript should be accompanied by "Copyright Transfer Agreement" prior to the article publication.