KADAR FERITIN PASIEN COVID-19

Dewi Astuti; Fuas Sitisari; Dewi Yunita; Eva Ayu Maharani

doi:10.59946/jfki.2023.169

FERITINE LEVELS IN COVID-19 PATIENTS

Dewi Astuti Poltekkes Kemenkes Jakarta III
Fuas Sitisari
Dewi Yunita
Eva Ayu Maharani

DOI: https://doi.org/10.59946/jfki.2023.169

Keywords: Keyword: COVID-19; Feritin; ICU

Abstract

Bacground: Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2). COVID-19 causes death both in the world and in Indonesia. Ferritin is an iron storage protein, whose levels can increase during viral infection and can be a marker of viral replication.Methdes: The study design used was a cross-sectional study of 592 secondary data of COVID-19 patients undergoing treatment in the ICU and hospitalizations who carried out ferritin examinations from January to December 2021 at Persahabatan Hospital. Research data were analyzed using the Mann-Whitney Test.Results: The mean value of ferritin levels in ICU patients was 2,406.7 ng/mL and inpatients was 1,249.6 ng/mL. The results of the Mann-Whitney Test obtained a p value of 0.000 <0.05 so that Ho was rejected, which means that there was a significant difference between ferritin levels in patients treated in the ICU and hospitalized at Persahabatan Hospital.Conclusion: There is a significant difference between ferritin levels in COVID-19 patients treated in the ICU and hospitalized in Persahabatan Hospital. Examination of ferritin levels can indicate severe inflammation in COVID-19 patients.

References

[1] Baraboutis IG, Gargalianos P, Aggelonidou E, Adraktas A. Pengalaman kehidupan nyata awal dari Pusat COVID-19 yang ditunjuk di Athena. Yunani: algoritme terapi yang diusulkan. SN Compr Clin Med. 2020;1-5.
[2] Dimopoulos, G., de Mast, Q., Markou, N., Theodorakopoulou, M., Komnos, A., Mouktaroudi, M., Netea, M. G., Spyridopoulos, T., Verheggen, R. J., Hoogerwerf, J., Lachana, A., van de Veerdonk, F. L., & Giamarellos- Bourboulis, E. J. (2020). Favorable Anakinra Responses in Severe Covid-19 Patients with Secondary Hemophagocytic Lymphohistiocytosis. Cell Host and Microbe, 28(1), 117-123.e1. https://doi.org/10.1016/j.chom.2020.05.007
[3] Hikmawati, I., & Setiyabudi, R. (2020). Hipertensi Dan Diabetes Militus Sebagai Penyakit Penyerta Utama Covid-19 Di Indonesia Hypertension and Diabetes Mellitus As Covid-19 Comorbidities in Indonesia. Prosiding Seminar Nasional Lppm Ump, 0(0), 95–100.
[4] Keputusan Menteri Kesehatan Republik Indonesia. (2020). Keputusan Menteri Kesehatan Republik Indonesia Nomor HK.01.07/MenKes/413/2020 Tentang Pedoman Pencegahan dan Pengendalian Corona Virus Disease 2019 (Covid- 19). MenKes/413/2020, 2019, 207.
[5] Linlin Cheng et all. Ferritin in the coronavirus disease 2019 (COVID-19): A systemic review and meta-analysis. J. Clin Lab Anal. 2020 Okt 34(10), 1-18.
[6] Sun, P., Lu, X., Xu, C., Sun, W., & Pan, B. (2020). Understanding of COVID-19 based on current evidence. Journal of Medical Virology, 92(6), 548–551. https://doi.org/10.1002/jmv.25722
[7] Susilo, A., Rumende, C. M., Pitoyo, C. W., Santoso, W. D., Yulianti, M., Sinto, R., Singh, G., Nainggolan, L., Nelwan, E. J., Khie, L., Widhani, A., Wijaya, E., Wicaksana, B., Maksum, M., Annisa, F., Jasirwan, O. M., Yunihastuti, E., Penanganan, T., New, I., … Cipto, R. (2020). Coronavirus Disease 2019 : Tinjauan Literatur Terkini Coronavirus Disease 2019 : Review of Current Literatures. Jurnal Penyakit Dalam Indonesia, 7(1), 45–67.

Published

2023-05-23

How to Cite

Astuti, D., Sitisari, F., Yunita, D., & Maharani, E. (2023). FERITINE LEVELS IN COVID-19 PATIENTS. Jurnal Fisioterapi Dan Kesehatan Indonesia, 3(1), 136-140. https://doi.org/10.59946/jfki.2023.169

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Electronic Preprints. Before submitting an article to an MEV Journal, authors frequently post their manuscripts to their own web site, their employer’s site, or to another server that invites constructive comment from colleagues. Upon submission of an article to MEV Journal, an author is required to transfer copyright in the article to RCEPM-LIPI, and the author must update any previously posted version of the article with a prominently displayed RCEPM-LIPI copyright notice. Upon publication of an article by the RCEPM-LIPI, the author must replace any previously posted electronic versions of the article with either (1) the full citation to the work with a Digital Object Identifier (DOI) or link to the article abstract in MEV journal homepage, or (2) the accepted version only (not the final, published version), including the RCEPM-LIPI copyright notice and full citation, with a link to the final, published article in journal homepage.

4. Articles in Press (AiP) service

RCEPM-LIPI may choose to publish an abstract or portions of the paper before we publish it in the journal. Please contact our Production department immediately if you do not want us to make any such prior publication for any reason, including disclosure of a patentable invention.

5. Author/Employer Rights

If you are employed and prepared the article on a subject within the scope of your employment, the copyright in the article belongs to your employer as a work-for-hire. In that case, RCEPM-LIPI assumes that when you sign this Form, you are authorized to do so by your employer and that your employer has consented to the transfer of copyright, to the representation and warranty of publication rights, and to all other terms and conditions of this Form. If such authorization and consent has not been given to you, an authorized representative of your employer should sign this Form as the Author.

6. RCEPM-LIPI Copyright Ownership

It is the formal policy of RCEPM-LIPI to own the copyrights to all copyrightable material in its technical publications and to the individual contributions contained therein, in order to protect the interests of the RCEPM-LIPI, its authors and their employers, and, at the same time, to facilitate the appropriate re-use of this material by others. RCEPM-LIPI distributes its technical publications throughout the world and does so by various means such as hard copy, microfiche, microfilm, and electronic media. It also abstracts and may translate its publications, and articles contained therein, for inclusion in various compendiums, collective works, databases and similar publications

Every accepted manuscript should be accompanied by "Copyright Transfer Agreement" prior to the article publication.